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Simple one-pot green method for large-scale production of mesalamine, an anti-inflammatory agent
C. Vijaya Lakshmi, Naresh Kumar Katari and Sreekantha B. Jonnalagadda Green Processing and Synthesis 8(1) 320 (2019) https://doi.org/10.1515/gps-2018-0108
Synthesis, molecular docking, and pharmacological evaluation of N‐(2‐(3,5‐dimethoxyphenyl)benzoxazole‐5‐yl)benzamide derivatives as selective COX‐2 inhibitors and anti‐inflammatory agents
Design, Synthesis, and Biological Evaluation of Some Novel Pyrrolizine Derivatives as COX Inhibitors with Anti-Inflammatory/Analgesic Activities and Low Ulcerogenic Liability
A one-pot synthesis of indole-appended heterocycles as potent anti-inflammatory, analgesic, and CNS depressant agents
Sasidhar Balappa Somappa, Jaiprakash Sharnappa Biradar, Parveen Rajesab, Shaik Rahber and Mety Sundar Monatshefte für Chemie - Chemical Monthly 146(12) 2067 (2015) https://doi.org/10.1007/s00706-015-1476-x
Synthesis and QSAR study of novel anti-inflammatory active mesalazine–metronidazole conjugates
Roman N. Naumov, Siva S. Panda, Adel S. Girgis, Riham F. George, Michel Farhat and Alan R. Katritzky Bioorganic & Medicinal Chemistry Letters 25(11) 2314 (2015) https://doi.org/10.1016/j.bmcl.2015.04.023
Novel 1-[4-(Aminosulfonyl)phenyl]-1H-1,2,4-triazole derivatives with remarkable selective COX-2 inhibition: Design, synthesis, molecular docking, anti-inflammatory and ulcerogenicity studies
Gamal El-Din A.A. Abuo-Rahma, Mohamed Abdel-Aziz, Nahla A. Farag and Tamer S. Kaoud European Journal of Medicinal Chemistry 83 398 (2014) https://doi.org/10.1016/j.ejmech.2014.06.049
1-(4-Methoxyphenyl)-5-(3,4,5-trimethoxyphenyl)-1H-1,2,4-triazole-3-carboxamides: Synthesis, molecular modeling, evaluation of their anti-inflammatory activity and ulcerogenicity
Synthesis and investigation of anti-inflammatory activity of novel nitric oxide donating hybrid drugs
Shailesh L. Chandak, Amol S. Bansode, Prashant R. Murumkar, Monika G. Shinde and Kailash G. Bothara Medicinal Chemistry Research 22(7) 3510 (2013) https://doi.org/10.1007/s00044-012-0345-y
Synthesis and biological evaluation of isoxazolo[4,5-d]pyridazin-4-(5H)-one analogues as potent anti-inflammatory agents
Keriman Özadalı, Fügen Özkanlı, Sarthak Jain, Praveen P.N. Rao and Carlos A. Velázquez-Martínez Bioorganic & Medicinal Chemistry 20(9) 2912 (2012) https://doi.org/10.1016/j.bmc.2012.03.021
Aspirin Analogues as Dual Cyclooxygenase‐2/5‐Lipoxygenase Inhibitors: Synthesis, Nitric Oxide Release, Molecular Modeling, and Biological Evaluation as Anti‐Inflammatory Agents
Synthesis, anti-inflammatory activity and ulcerogenic liability of novel nitric oxide donating/chalcone hybrids
Gamal El-Din A.A. Abuo-Rahma, Mohamed Abdel-Aziz, Mai A.E. Mourad and Hassan H. Farag Bioorganic & Medicinal Chemistry 20(1) 195 (2012) https://doi.org/10.1016/j.bmc.2011.11.012
Ethanesulfohydroxamic Acid Ester Prodrugs of Nonsteroidal Anti-inflammatory Drugs (NSAIDs): Synthesis, Nitric oxide and Nitroxyl Release, Cyclooxygenase Inhibition, Anti-inflammatory, and Ulcerogenicity Index Studies
Zhangjian Huang, Carlos A. Velázquez, Khaled R. A. Abdellatif, Morshed A. Chowdhury, Julie A. Reisz, Jenna F. DuMond, S. Bruce King and Edward E. Knaus Journal of Medicinal Chemistry 54(5) 1356 (2011) https://doi.org/10.1021/jm101403g
Synthesis, Characterization, and Biological Evaluation of Novel Diclofenac Prodrugs
Babasaheb P. Bandgar, Rajendra Janardan Sarangdhar, Fakrudeen Ali Ahamed and Santosh Viswakarma Journal of Medicinal Chemistry 54(5) 1202 (2011) https://doi.org/10.1021/jm101095e
Synthesis and biological evaluation of some 1,3,4-oxadiazole derivatives
K. Manjunatha, Boja Poojary, Prajwal L. Lobo, Jennifer Fernandes and N. Suchetha Kumari European Journal of Medicinal Chemistry 45(11) 5225 (2010) https://doi.org/10.1016/j.ejmech.2010.08.039
Design, synthesis, and evaluation of anti-inflammatory, analgesic, ulcerogenicity, and nitric oxide releasing studies of novel indomethacin analogs as non-ulcerogenic derivatives
Shashikant V. Bhandari, Jignesh K. Parikh, Kailash G. Bothara, et al. Journal of Enzyme Inhibition and Medicinal Chemistry 25(4) 520 (2010) https://doi.org/10.3109/14756360903357585
Dinitroglyceryl and diazen-1-ium-1,2-diolated nitric oxide donor ester prodrugs of aspirin, indomethacin and ibuprofen: Synthesis, biological evaluation and nitric oxide release studies
Khaled R.A. Abdellatif, Morshed Alam Chowdhury, Ying Dong, Dipankar Das, Gang Yu, Carlos A. Velázquez, Mavanur R. Suresh and Edward E. Knaus Bioorganic & Medicinal Chemistry Letters 19(11) 3014 (2009) https://doi.org/10.1016/j.bmcl.2009.04.059
Second-Generation Aspirin and Indomethacin Prodrugs Possessing an O2-(Acetoxymethyl)-1-(2-carboxypyrrolidin-1-yl)diazenium-1,2-diolate Nitric Oxide Donor Moiety: Design, Synthesis, Biological Evaluation, and Nitric Oxide Release Studies
Carlos A. Velázquez, Qiao-Hong Chen, Michael L. Citro, Larry K. Keefer and Edward E. Knaus Journal of Medicinal Chemistry 51(6) 1954 (2008) https://doi.org/10.1021/jm701450q
Carlos A. Velázquez, P.N. Praveen Rao, Michael L. Citro, Larry K. Keefer and Edward E. Knaus Bioorganic & Medicinal Chemistry 15(14) 4767 (2007) https://doi.org/10.1016/j.bmc.2007.05.009